1. Windows 8
2. Oracle Virtualbox for Windows 4.3.26-98988
If you ever met this error “Error -5600 in supR3HardenedWinReSpawn!” and your Virtual Machine (VM) won’t start, not just one but all of them cannot start then you must check your Windows Update. If you want to know the detail just follow this Oracle Virtualbox – VM Cannot Start ntdll Error
After KB3045999 uninstalled your computer will reboot. After reboot try again your Oracle Virtualbox and voila it works again. FYI, KB3045999 is a security update. If you want to know the detail just search it.